a rare case of fixed drug eruption due to ondansetron

نویسندگان

aditi maitra department of clinical and experimental pharmacology, calcutta school of tropical medicine, kolkata, india;

shashwat bhattacharyya department of ophthalmology, calcutta national medical college, kolkata, india

sabyasachi paik department of clinical and experimental pharmacology, calcutta school of tropical medicine, kolkata, india;

prerna pathak department of dermatology and venereology, calcutta school of tropical medicine, kolkata, india

چکیده

abstract fixed drug eruption (fde) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. fde is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. a 27-year-old woman presented with multiple dark patches over her eyelids, mouth, lips, and shoulders of 1 week’s duration. these lesions followed multiple erythematous plaques over the same areas which appeared within 4 hours of the intake of an ondansetron tablet, 12 days previously. the case was diagnosed as post-inflammatory hyperpigmentation following ondansetron-induced fde. there was an identical episode 1 year earlier due to the intake of the same drug. the causality assessment pointed toward a probable/likely association as per the naranjo algorithm and the who–umc scale. there have been only a few cases of fde due to ondansetron in the reported literature.

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A Rare Case of Fixed Drug Eruption due to Ondansetron

AbstractFixed drug eruption (FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. FDE is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. A 27-year-old woman presented with multiple dark patches over her eyelids...

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عنوان ژورنال:
iranian journal of medical sciences

جلد ۴۱، شماره ۲، صفحات ۰-۰

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